The Rabbit Anti-Pragmin Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PRAG1. This antibody recognizes Human, Mouse, and Rat antigen. The Rabbit Anti-Pragmin Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity). Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity). Acts as a critical coactivator of Notch signaling (By similarity)